REVO Research & Development Freeze Dryer

The REVO Research & Development Freeze Dryer has the largest shelves and best shelf-to-shelf spacing of any freeze dryer in its class offering up to 10 sq ft (0.989 sq M) of shelf area and a condensing rate of 20 Liters in 24 hours. This allows for more product throughput in the same floor space. Using the best components and design techniques combined with the most advanced PC/PLC control system, the REVO R&D Lyophilizer offers data collection and self-testing features. Overall, the REVO R&D Freeze Dryer is the perfect solution for both your protocol development and small scale lyophilization production needs.

Our easy-to-use software provides automatic freeze drying, defrost, system and leak rate testing. Data can be printed either numerically or graphically. This same control system is used on industrial dryers, allowing scaling to production. An interactive maintenance screen simplifies component servicing. All systems are remotely accessible, with customer approval, for trouble-shooting process issues.


SPECIFICATIONS

CONTROL SYSTEM

  • PC/PLC with ethernet and remote Internet connectivity
  • Manual and automatic operating modes
  • Graphic and numeric data collection
  • Automatic System and Leak Rate Testing
  • Options for Protocol Optimization and Controlled Nucleation

 SHELF SYSTEM

  • Up to 10 sq. ft. (0.989 sq M) of shelf area
  • Large shelves for more product capacity – 12″ x 24″ (30,4cm x 61cm)
  • Increased Stoppering Pressure – for 2ml vials
  • 316L stainless steel on all wetted parts

 CONDENSER

  • 6″ vapor port standard
  • Exposed coil condenser for maximum efficiency
  • Hot gas defrost

 REFRIGERATION

  • High reliability scroll compressors
  • Oversized refrigeration components for high reliability
  • CFC-Free, non-proprietary refrigerants

VACUUM

  • Pirani vacuum sensor standard
  • Vacuum control standard
  • Gas backfill standard
  • 375 lpm corrosion resistant vacuum pump

 OTHER

  • Sanitary style fittings on all sensor and vacuum ports
  • Built-in validation port

Note: Specifications subject to change without notice. All specifications based on 20C ambient on 60Hz.

REVO STANDARD FEATURES

SHELF AREA 2 sq. ft. (0,185 sq M) to 10 sq. ft. (0.989 sq M)
SHELF ASSEMBLY Bulk or Hydraulic Stoppering
SHELF TEMPERATURE RANGE -45ºC or -70º to + 65°C
SHELF HEAT TRANSFER Hollow Fluid Filled
SHELF SIZE/FINISH 12″x 24″(30,4cm x 61cm), 316L, 20 Ra or better
VAPOR PORT 6″ (15 cm) Standard
CONDENSER TEMP -53°C or -85°C
CONDENSER CAPACITY 30L
CONDENSING RATE 20L in 24 hours
CONDENSER STYLE Exposed Coil
DEFROST Hot Gas
COMPRESSORS (SCROLL) 3.5hp (-53ºC), 3.5hp & 2hp (-85°C)
PRODUCT SENSORS 4, Type T thermocouple
VACUUM PUMP 375 lpm, Corrosion Resistant
VACUUM CONTROL Pirani w/ Solenoid & Needle Valve
GAS BACKFILL included
CONTROL SYSTEM PC/PLC with Opti-Dry Software
TRAYS One per shelf included
CABINET 35″w x 46″d x 75″h (89 cm x 117 cm x 190 cm)
ELECTRICAL 240V/1ph/50Hz/30A (-53°C)
400V/3ph/50hZ

VIAL CAPACITY

VIAL
(ml)
DIA
(mm)
HT
(mm)
# Shelves
1 2 3 4 5
2 16 41 774 1548 2322 3096 3870
5 22 48 403 806 1209 1612 2015
10 24 58 322 644 966 1288
20 29 71 218 436 654
50 43 81 96 192
100 52 92 65 130

* Capacity data shown in the above chart is an approximation.


SHELF CONFIGURATION

Shelves Spacing
(in/mm)
Area
(sq ft/sq M)
1 14.5 / 368 2 / 0.186
2 7.0 / 177 4 / 0.373
3 4.5 / 114 6 / 0.559
4 3.25 / 82 8 / 0.746
5 2.5 / 63 10 / 0.932

BULK FILL

DEPTH 1 2 3 4 5
10mm 1.8 3.6 5.4 7.2 9.0
15mm 2.7 5.4 8.1 10.8 13.5
20mm 3.6 7.2 10.8 14.4 18.0

* Capacity data shown in the above chart is an approximation.


OPTI-DRY® PC/PLC CONTROL

The REVO R&D Lyophilizer comes complete with PLC controls and a PC for programming and data collection. Our easy-to-use software provides automatic freeze-drying, defrost, and system test. Data can be printed either numerically or graphically. This same control system can be used on industrial dryers, allowing scaling to production. An interactive maintenance screen simplifies component servicing.

OPTI-DRY uses an Ethernet platform for hardware connectivity making data transmission extremely fast. It also provides web connectivity for those who want remote access to their systems.

For R&D, Protocol Development, Small Scale Freeze Drying Production, Cycle Automation, Opti-Dry offers all the tools you need.


AVAILABLE OPTIONS

• Water Defrost
• Up to 16 Product Probes
• Capacitance Manometer
• Proportional Vacuum Control
• Dry Vacuum Pump
• Isolation Valve
• Stainless Steel Doors
• Shelf Latching Kit
• LN2 Trap
• Water Cooled Condenser
• Resistivity Probe
• Spider Sample Extractor
• Millrock Reporter – Batch Reporting
Clean in Place (CIP) Video *** Requires Narrow Configuration
• Clean Room Configuration
• Isolator Interface
• H2O2 Integration Kit
• 21 CFR Part 11 Software
• Validation Documentation
• IQ/OQ Workbook
• FAT/SAT
• Pressure Rise Testing (requires isolation valve)

More information

The REVO R&D Freeze Dryer has been developed from over 50 years of experience in the freeze drying world. The standard system design provides a highly reliable platform for your freeze drying needs. Using more robust refrigeration components ensures the highest performance and reliability available. In addition, the system is designed to be more tolerant of fluctuations in room temperature and supply voltage, which are common issues with lower end systems.

Unique design with features include: more accurate vacuum sensors; no rubber hoses; no vapor flow choke points; superior shelf temperature uniformity; reduced shelf temperature transition times; increased stoppering pressure; and more, to ensure that the equipment is not a limit to your freeze drying needs.

 

Need further information?

Don’t hesitate to contact us, our customer service representatives are happy to help! Just fill in the contact form and we will get back to you as soon as possible. Use the link below to get in touch with us.

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Contact us

ITALIAN OFFICE

Via A. Pacinotti, 19 05100 - Terni, Italy
+39 075 9729017 / info@pharma-tech.it

 

CONTACT NAMES

Stefano Montagnoli - CEO
Mobile Phone: +39 335 8078512
Mail: stefano.montagnoli@pharma-tech.it

Sanesi Paolo - Technical Director
Mobile Phone:+39 348 3345859
Mail: paolo.sanesi@pharma-tech.it